ncRNA name | Cyld shRNA |
ncRNA Category | shRNA |
Disease name | retinal detachment |
Species | Rattus norvegicus |
Tissues/Cell_line | retinas |
Methods | shRNA injection, H&E staining, fluorescence detection, PI staining, ERG, immunoprecipitation, Western blot |
Expression pattern | associated |
Functional description | Knockdown of cylindromatosis expression led to inhibition of caspase 8 activity, a decrease in the number of apoptotic photoreceptor cells, and an increase in the ubiquitination level of receptor-interacting protein 1. |
PubMed ID | 28633009 |
Year | 2017 |
Title | RNA Interference Reveals the Coregulatory Effects of Cylindromatosis on Apoptosis and Necroptosis of Photoreceptor Cells in Experimental Retinal Detachment. |
Drug-related ncRNA | NA |
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